The Research

The peer-reviewed work Lune is built on.

Cycle-based training is real science — and also an evolving one. Here's the work that shapes how Lune programs. We'll keep adding papers as the field grows.

2020Sports MedicineMeta-analysis · 78 studies

The Effects of Menstrual Cycle Phase on Exercise Performance in Eumenorrheic Women

McNulty KL, Elliott-Sale KJ, Dolan E, et al.

Across 78 studies, performance dips during the early follicular phase (your period) are real — but small. What's big is the variation between women. This is why Lune uses recovery and symptom context alongside cycle phase instead of applying a one-size template.

Read on PubMed →
2020Sports MedicineMeta-analysis · 42 studies

The Effects of Oral Contraceptives on Exercise Performance in Women

Elliott-Sale KJ, McNulty KL, Ansdell P, et al.

The largest meta-analysis on oral contraceptives and performance found no meaningful gap between pill users and naturally cycling women — and no day-of-the-pill penalty. This is why Lune has a dedicated mode for hormonal birth control: instead of chasing phantom phases, it shifts programming to your daily recovery, symptom, and energy signals — the inputs that actually matter when your natural cycle is suppressed.

Read on PubMed →
2014SpringerPlusRandomized trial

Effects of Follicular Versus Luteal Phase-Based Strength Training in Young Women

Sung E, Han A, Hinrichs T, Vorgerd M, Manchado-Gobatto C, Platen P

Same woman, one leg trained in follicular phase, the other in luteal. The follicular-trained leg gained more strength and more muscle diameter. This is part of the evidence behind why Lune scores imported programs against cycle context instead of pretending phase never matters.

Read on PubMed →
2017J Sports Med Phys Fitness4-month trial

Effects on Power, Strength and Lean Body Mass of Menstrual/Oral Contraceptive Cycle–Based Resistance Training

Wikström-Frisén L, Boraxbekk CJ, Henriksson-Larsén K

Four months of cycle-periodized resistance training in trained women. Loading hard sessions into the first two weeks of the cycle beat both luteal-concentrated and evenly-spread training for several outcomes. This is the kind of periodization evidence Lune draws from when it frames training around cycle context.

Read on PubMed →
2022Sports MedicineReview

Effects of Follicular and Luteal Phase-Based Menstrual Cycle Resistance Training on Muscle Strength and Mass

Kissow J, Jacobsen KJ, Gunnarsson TP, Jessen S, Hostrup M

The most recent critical review of the field. It suggests follicular-phase resistance training may produce better strength and mass gains, while also calling out the literature's real limitations. Lune takes that as a cue to treat phase as one input alongside recovery and symptoms — not as a rigid script.

Read on PubMed →
2017Orthop J Sports MedMeta-analysis · 68,758 participants

The Effect of Menstrual Cycle and Contraceptives on ACL Injuries and Laxity

Herzberg SD, Motu'apuaka ML, Lambert W, Fu R, Brady J, Guise JM

68,758 women studied. Knee ligament laxity spikes during ovulation. Non-contact ACL injuries cluster outside the luteal phase. Oral contraceptives may cut injury risk by ~20%. The product takeaway for Lune is caution: this is a useful risk signal, but not a license to pretend every knee needs the exact same ovulation-week programming.

Read on PubMed →
2010Sports MedicineReview

The Effect of the Menstrual Cycle on Exercise Metabolism

Oosthuyse T, Bosch AN

Your body burns fuel differently across the cycle — more fat oxidation and stronger endurance in the mid-luteal phase when the estrogen:progesterone ratio peaks. This is part of why cycle-aware coaching around training, recovery, and fueling context can matter.

Read on PubMed →
2003Sports MedicineReview

Effects of the Menstrual Cycle on Exercise Performance

Janse de Jonge XAK

A landmark review with a counterintuitive finding: when methodology is tight, your muscles aren't necessarily weaker on your period. The product takeaway is that menstruation alone shouldn't force a blanket "go easy" rule — context still matters.

Read on PubMed →
2018IJSNEMReview

Endocrine Effects of Relative Energy Deficiency in Sport (RED-S)

Elliott-Sale KJ, Tenforde AS, Parziale AL, Holtzman B, Ackerman KE

Low energy availability — eating less than your training demands — suppresses reproductive hormones, accelerates bone loss, and tanks performance. This is an important risk in women's performance, but Lune does not currently diagnose or flag RED-S-style patterns in product.

Read on PubMed →
2005Clinics in Sports MedicineReview

The Menstrual Cycle and Sport Performance

Constantini NW, Dubnov G, Lebrun CM

The clinical foundation. Maps how estrogen and progesterone interact with metabolism, thermoregulation, psychology, and injury risk across every cycle phase. The phase ring you see inside Lune — menstrual, follicular, ovulatory, luteal, each with its own energy profile and training implications — traces directly back to papers like this one.

Read on PubMed →

This field is still young relative to male-focused sports science. Some findings are robust (early-follicular performance dips are small, ovulatory knee laxity is real); others are active areas of debate. Lune errs toward individual adaptation over rigid templates, and we update our programming as the evidence moves.

Ready to train with the research, not against it?

Lune turns this work into adaptive, cycle-aware programming — without making you read the papers yourself.

Join the Waitlist